November 19, 2013
Bioengineers at the University of California, San Diego have used the genomic sequences of 55 E. coli strains to reconstruct the metabolic repertoire for each strain. Surprisingly, these reconstructions do an excellent job of predicting the kind of environment where each strain will thrive, the researchers found.
October 7, 2021
…uncovering the mechanisms behind staph infections, strep throat, and irritable bowel syndrome. “Everyone wants to Gonzalez-ify their research,” said Nizet. A mentor-turned-colleague, Nizet praises Gonzalez’s ability to bring scientists together and encourage them to take risks for the greater good. Gonzalez celebrated completing his Ph.D. with a piñata outside the…
December 12, 2024
As 2024 comes to a close, we reflect on a remarkable year of research that pushed the boundaries of knowledge and innovation.
October 10, 2024
UC San Diego has received a $7 million ARPA-H contract for the PROTECT project, targeting pathogens like Pseudomonas aeruginosa and Staphylococcus aureus. These pathogens pose serious health risks to individuals with cystic fibrosis and those reliant on respirators.
October 18, 2022
Victor Nizet, MD, Distinguished Professor of Pediatrics at University of California San Diego School of Medicine and Pharmacy at Skaggs School of Pharmacy and Pharmaceutical Sciences, has been elected to the National Academy of Medicine.
October 13, 2015
Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments. Tamoxifen treatment in mice also…
January 26, 2016
Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. The mouse study is published January 25…
December 16, 2024
After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model.
July 3, 2024
Researchers at University of California San Diego show that a molecule which shuttles damaging inflammatory cells into cancer tumors also shuttles inflammatory cells into lung tissue infected with COVID-19 — and that the molecule can be suppressed with a repurposed cancer drug. The work represents a new approach to preventing…
January 4, 2016
A team of researchers, with the aid of the Gordon supercomputer at the San Diego Supercomputer Center based at UC San Diego, has identified a class of possible antibiotics with the potential to disable previously drug-resistant bacteria.
