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Your search for “Staph Infection” returned 41 results

We Need a Staph Vaccine: Here’s Why We Don’t Have One

January 16, 2024

A vaccine for Staphylococcus aureus, one of the most common bacterial infections, would be a game changer for public health. No vaccine candidates have succeeded in clinical trials, but nobody knows why. Researchers at UC San Diego may have figured it out.

Distinguishing Deadly Staph Bacteria from Harmless Strains

June 6, 2016

…understand the pathogenic bacteria Staphylococcus aureus and develop more effective treatments, University of California San Diego researchers examined the Staph “pan-genome” — the genomes of 64 different strains that differ in where they live, the types of hosts they infect and their antibiotic resistance profiles. This effort, published June 6…

Familiarity Breeds Exempt: Why Staph Vaccines Don’t Work in Humans

July 7, 2022

UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.

Nanosponge Vaccine Fights MRSA Toxins

December 2, 2013

…produced by MRSA (methicillin-resistant Staphylococcus aureus) could serve as a safe and effective vaccine against this toxin. This “nanosponge vaccine” enabled the immune systems of mice to block the adverse effects of the alpha-haemolysin toxin from MRSA—both within the bloodstream and on the skin. Nanoengineers from the University of California,…

UC San Diego Pharmacist’s Work Helps Save Lives Across the Globe

August 27, 2020

…with COVID-19, a viral infection, may be prescribed vancomycin due to the critical nature of their illness. “What often happens is a patient who spends a long time in the hospital may develop blood or lung infections with antibiotic-resistant bacteria known as MRSA—that’s short for methicillin-resistant Staphylococcus aureus, sometimes also…

Fat Isn’t All Bad: Skin Adipocytes Help Protect Against Infections

January 5, 2015

…it comes to skin infections, a healthy and robust immune response may depend greatly upon what lies beneath. In a new paper published in the January 2, 2015 issue of Science, researchers at the University of California, San Diego School of Medicine report the surprising discovery that fat cells below…

Machine Learning Identifies Antibiotic Resistance Genes in Tuberculosis-Causing Bacteria

October 25, 2018

…approach could be used to predict resistance in other infection-causing pathogens.

Repurposed Heart and Flu Drugs May Help Body Fight Sepsis

March 24, 2021

UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.

How to Spot Patients Most Likely to Die from Blood Infections

September 3, 2020

…to Die from Blood Infections David Gonzalez’s “a-ha” moment came when a physician-colleague, George Sakoulas, MD, shared with him one of the biggest problems faced in clinical practice: How long it takes to diagnose a patient. “The faster we know what’s going to happen to our patients, the better we…

Therapeutic Potential of Bizarre ‘Jumbo’ Viruses Tapped for $10M HHMI Emerging Pathogens Project

January 26, 2023

UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.

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