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Your search for “Liver Disease” returned 205 results

UC San Diego Health Named Center of Excellence for Polycystic Kidney Disease

December 13, 2022

UC San Diego Health has been named a Center of Excellence for polycystic kidney disease (PKD) by the PKD Foundation – the leading advocacy group dedicated to finding treatments and a cure for PKD. UC San Diego Health is one of just 28 institutions nationwide to receive this designation.

Medical Innovator: Farah Sheikh

April 1, 2024

UC San Diego researcher, Farah Sheikh, studies a genetic heart arrhythmia condition that usually strikes people under 40. Her research will be used in clinical trials of a treatment for ARV.

Knocking Out Key Protein in Mice Boosts Insulin Sensitivity

November 10, 2011

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

Friedmann Recognized for Pioneering Gene Therapy Research

January 29, 2015

…therapy for human genetic disease?” Though posed as a question, Friedmann and Roblin firmly believed the answer was yes, citing emergent thinking, new studies and growing data that suggested “good DNA” could be used to replace defective DNA in people with inherited conditions. “In our view,” they wrote, “gene therapy…

Single Enzyme’s Far-Reaching Influence in Human Biology and Disease

June 18, 2015

Researchers at University of California, San Diego School of Medicine have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C. The finding is published June 18 by Cell.

Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment

February 10, 2020

UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.

Rethinking Remdesivir

August 2, 2021

UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.

Nanosponges Soak Up Toxins Released by Bacterial Infections and Venom

April 14, 2013

Engineers at the University of California, San Diego have invented a “nanosponge” capable of safely removing a broad class of dangerous toxins from the bloodstream – including toxins produced by MRSA, E. coli, poisonous snakes and bees.

At the Front Lines of San Diego’s Hepatitis A Outbreak

October 12, 2017

…people who suffer from liver diseases (cirrhosis, hepatitis B or hepatitis C), people who have clotting factor disorders, and those traveling to countries that have high hepatitis A rates. Health care, social and public health workers are also at increased risk. The vaccine is being provided to UC San Diego…

Repurposed Heart and Flu Drugs May Help Body Fight Sepsis

March 24, 2021

UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.

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