November 10, 2011
By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.
January 29, 2015
…therapy for human genetic disease?” Though posed as a question, Friedmann and Roblin firmly believed the answer was yes, citing emergent thinking, new studies and growing data that suggested “good DNA” could be used to replace defective DNA in people with inherited conditions. “In our view,” they wrote, “gene therapy…
June 18, 2015
Researchers at University of California, San Diego School of Medicine have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C. The finding is published June 18 by Cell.
February 10, 2020
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
August 2, 2021
UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.
April 14, 2013
Engineers at the University of California, San Diego have invented a “nanosponge” capable of safely removing a broad class of dangerous toxins from the bloodstream – including toxins produced by MRSA, E. coli, poisonous snakes and bees.
October 12, 2017
…people who suffer from liver diseases (cirrhosis, hepatitis B or hepatitis C), people who have clotting factor disorders, and those traveling to countries that have high hepatitis A rates. Health care, social and public health workers are also at increased risk. The vaccine is being provided to UC San Diego…
March 24, 2021
UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.
March 22, 2016
The Hemophilia and Thrombosis Treatment Center at UC San Diego Health has joined a nationwide clinical trial testing a potential gene therapy that may one day provide a better and long-lasting treatment for people with hemophilia B.
February 7, 2023
UC San Diego Health’s Center for Transplantation is among the nation’s best in lung, heart, kidney and liver programs, powered by long experience and deep expertise.
