Scientists Discover a New Signaling Pathway and Design a Novel Drug for Liver Fibrosis
April 25, 2024
Scientists from the University of California San Diego discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis.
Your search for “Liver Disease” returned 198 results
New Living Donor Option for Liver Transplantation at UC San Diego Health
March 1, 2016
Nationally, more than 15,000 patients are waiting for a liver transplant. Approximately 6,300 persons each year will receive a new liver; 1,400 die waiting. In California, one in four listed for liver transplant will die before an organ becomes available. Fortunately, living donation is now a lifesaving option at UC…
Domino Liver Transplant Treats Two Rare Diseases, World First
September 21, 2011
For the first time ever, a surgical team led by Alan Hemming, MD, has successfully performed a domino transplant using a liver with a rare genetic disorder called methylmalonic acidemia (MMA).
Researchers Illuminate Key Role of NOX Proteins in Liver Disease
July 29, 2015
Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.
Math Equation Predicts and Detects Liver Cancer
December 16, 2019
University of California San Diego School of Medicine and Moores Cancer Center researchers developed a math equation to predict and detect liver cancer and identified when healthy cells become cancerous.
Diet Plays Critical Role in NASH Progressing to Liver Cancer in Mouse Model
June 1, 2021
Researchers at University of California San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.
Newly Discovered Cells Regenerate Liver Tissue Without Forming Tumors
August 13, 2015
…mechanisms that allow the liver to repair and regenerate itself have long been a matter of debate. Now researchers at University of California, San Diego School of Medicine have discovered a population of liver cells that are better at regenerating liver tissue than ordinary liver cells, or hepatocytes. The study…
Radical Surgery Saves Life of Young Mom, California First
January 18, 2012
…Young Mom, California First Liver Removed, Reconstructed, Re-Implanted A team led by Dr. Alan Hemming, a transplant surgeon at UC San Diego Health System, has successfully performed the West Coast’s first ex-vivo liver resection, a radical procedure to completely remove and reconstruct a diseased liver and re-implant it without any…
High Levels of Protein p62 Predict Liver Cancer Recurrence
May 19, 2016
…that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival. In mice, they also found that p62 is required for liver cancer to form.
Alcohol Use Can Alter Gut Microbes, but Not in the Way You Might Think
August 11, 2022
In mouse studies, UC San Diego researchers find that excess alcohol consumption alters gut microbiome but latter is not directly or significantly linked to liver disease.
