February 24, 2021
UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.
November 22, 2013
Researchers at the University of California, San Diego School of Medicine have shown for the first time how influenza A viruses snip through a protective mucus net to both infect respiratory cells and later cut their way out to infect other cells.
April 28, 2021
UC San Diego School of Medicine researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.
August 20, 2020
…challenging to fight viral infections such as influenza or perhaps COVID-19. HIV may result in increased susceptibility to secondary illnesses such as pneumonia, heart and lung diseases and death. “I took all the precautions to protect myself, so I never thought I would get it,” said Anna. An essential worker,…
June 6, 2013
Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease.
April 2, 2021
UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.
June 8, 2021
Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.
November 18, 2021
…approaching, concerns about COVID-19 infections are on the rise. But despite increasing access to vaccines and booster shots, one group continues to show low vaccination rates. Only one-third of pregnant people are fully vaccinated in the U.S., and the rates are even lower for pregnant people of color. These numbers…
July 25, 2018
In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.
October 17, 2017
Two recent studies led by UC San Diego biologists have set the research groundwork for new avenues to treat influenza and anthrax poisoning. Published in PLOS Pathogens, the studies from Professor Ethan Bier’s laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in…
