September 22, 2022
UC San Diego engineers developed microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia. In mice, the microrobots safely eliminated pneumonia-causing bacteria in the lungs and resulted in 100% survival.
August 31, 2021
UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.
September 14, 2021
Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.
April 29, 2020
UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.
June 11, 2021
UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.
December 10, 2019
People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.
March 20, 2019
Researchers from the University of Michigan relied on supercomputers at UC San Diego and elsewhere to help them develop detailed models to better understand how TB spreads throughout the lungs.
September 26, 2018
…Sciences report that tweaking factors in a cystic fibrosis lung model, such as pH balance and oxygen, helped eradicate pathogenic bacteria while minimizing risks of antibiotic resistance and overgrowth of other microorganisms.
October 11, 2022
UC San Diego scientists are leading a national early-stage clinical trial to assess the safety and efficacy of using bacteriophages to treat drug-resistant bacterial infections in cystic fibrosis patients.
July 20, 2022
UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.