November 14, 2019
Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.
July 12, 2021
Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.
August 19, 2021
UC San Diego researchers detail how a ubiquitous signaling molecule plays a critical role in male fertility, orchestrating key steps that promote sperm motility, survival and fertilization success.
May 16, 2022
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
July 20, 2022
UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.
June 8, 2023
Biologists have identified a previously unknown way that our immune system detects viruses. The immune protein CARD8 acts as a trip wire to detect a range of viruses, including the virus that causes COVID. They also found that CARD8 functions differently among species and varies between humans.
June 4, 2024
A group of researchers at University of California San Diego has identified the cause of a “short-circuit” in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development of a wide array of new drugs.
