Controlling Cholesterol in Microglia Alleviates Chronic Pain, Opioid-Free
May 10, 2021
Using a mouse model, researchers discover pivotal role of cholesterol in chronic pain often caused by chemotherapy, and propose novel therapy.
Your search for “Genetics” returned 1146 results
Superficial Relationship: Enzymes Protect the Skin by Ignoring Microbes and Viruses
May 21, 2021
UC San Diego School of Medicine researchers identify how the body regulates and prevents constant skin inflammation.
UC San Diego Health Begins Treating Multiple Myeloma with CAR T-cell Therapy
June 3, 2021
As the first designated medical center in San Diego certified to offer this type of immunotherapy, UC San Diego Health will begin treating patients this month.
Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins
July 2, 2021
UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.
Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery
July 12, 2021
Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.
Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects
August 12, 2021
A new cancer immunotherapy pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The approach could make chimeric antigen receptor (CAR) T-cell therapy safer and effective at treating solid tumors.
A Target for Potential Cancer Drugs May, In Fact, Worsen Disease
November 9, 2021
Researchers reveal a previously unrealized complexity in cancer development, one that raises concerns and caution about targeting an enzyme popular in oncological treatments.
State Stem Cell Agency Awards $4M for Blood Cancer Immunotherapy at UC San Diego
November 24, 2021
The California Institute for Regenerative Medicine (CIRM) approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.
Nuclei-free Cells Prove Utility in Delivering Therapeutics to Diseased Tissues
January 14, 2022
UC San Diego researchers report successfully removing the nucleus from a type of ubiquitous cell, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.Researchers at University of California San Diego School of Medicine and Moores
Alcohol Use Linked to Lower Connectivity in Brain Areas that Process Emotions
February 8, 2022
People at risk of developing alcohol use disorder show lower functional connectivity between brain regions involved in processing facial expressions. Future psychoeducation programs focused on improving social and emotional processing may help prevent alcohol use disorder.
