March 21, 2017
An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer’s disease (AD), based upon genetic information.
October 11, 2013
…of the National Institutes of Health, to elucidate the genetics of glaucoma in persons of African descent.
June 16, 2022
Computer scientist Vineet Bafna is part of a team of world-class researchers that has been awarded a five-year, $25 million grant to learn how the destructive genetic lesion extrachromosomal DNA (ecDNA) influences numerous cancers and to identify possible therapies.
August 15, 2017
Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.
March 5, 2018
…researchers has developed a light-activated switch that can turn genes on and off in mammalian cells. This is the most efficient so-called “optogenetic switch” activated by red and far-red light that has been successfully designed and tested in animal cells—and it doesn’t require the addition of sensing molecules from outside…
November 12, 2013
A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression.
March 13, 2012
Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential treatment for prostate cancer, using a drug currently marketed for congestive heart failure.
September 10, 2020
UC San Diego researchers describe how the functional loss of a single gene negatively impacts neural development and promotes the growth of a particularly deadly form of pediatric brain cancer.
April 30, 2014
…with colleagues in Norway, significantly refines the association, highlighting genetic risk factors associated with low density lipoprotein (LDL) cholesterol and triglycerides as key players and identifying 17 related gene loci that make risk contributions to levels of these blood lipids and to prostate cancer.
October 13, 2021
UC San Diego researchers report that conducting genomic evaluations of advanced malignancies can be effective in guiding first-line-of-treatment, rather than waiting until standard-of-care therapies have failed.
