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Your search for “Gene Therapy” returned 765 results

Gene Therapy Approach Shows Promise in Treating ALS

August 2, 2022

Researchers report that a gene therapy approach, developed at UC San Diego measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

May 2, 2022

UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.

Personalizing Precision Medicine with Combination Therapies Improves Outcomes in Cancer

April 22, 2019

University of California San Diego School of Medicine researchers found that treating patients with personalized precision medicine that combined therapies to target multiple alterations improved outcomes in patients with therapy resistant cancers.

Non-Coding DNA Located Outside Chromosomes May Help Drive Glioblastoma

November 21, 2019

According to a new Cell study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going — elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat.

Discovery of Wound-Healing Genes in Flies Could Mitigate Human Skin Ailments

April 24, 2013

Biologists at UC San Diego have identified eight genes never before suspected to play a role in wound healing that are called into action near the areas where wounds occur.

Long-Reads and Powerful Algorithms Identify “Invisible” Microbes

January 3, 2022

Researchers have shown that highly accurate, long-read genomic sequencing technology (HiFi), combined with advanced algorithms, can differentiate between nearly identical organisms, allowing researchers to more completely catalogue microbial communities.

Personalized Cancer Therapy Improves Outcomes in Advanced Disease, Says Study

October 2, 2020

Patients receiving care for advanced cancer at Moores Cancer Center at UC San Diego Health were more likely to survive or experience a longer period without their disease progressing if they received personalized cancer therapy.

Alternative Proteins Encoded by Same Gene Have Widely Divergent Functions

February 11, 2016

A single human gene can produce many different proteins. In the first large-scale study of its kind, researchers at University of California, San Diego School of Medicine, Dana-Farber Cancer Institute and McGill University report that most of these sibling proteins encoded by the same gene — known as protein isoforms…

UC San Diego/SDSC Study Advances Brain Cancer Research

February 11, 2015

Researchers at the San Diego Supercomputer Center (SDSC), Moores Cancer Center, and Department of Neurosciences at the University of California, San Diego, have shown for the first time a pyramid hierarchical network of “coherent gene modules” that regulate glioblastoma genes, involved in a highly aggressive form of brain cancer.

UC San Diego-Human Longevity Inc. Agreement Seeks to Accelerate Medical Science

March 4, 2014

…to research and translate the potential of the human genome into novel and real treatments and therapies able to change and improve the human condition.

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