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Your search for “Drug Development” returned 941 results

High R&D Isn’t Necessarily Why Drugs Are So Expensive

September 26, 2022

In the first known study of its type, an international team of researchers evaluated whether high research and development costs explain high drug prices in the United States. They found no such association for 60 new drugs approved from 2009 to 2018.

New Drug Screening Method Answers Why Alzheimer’s Drugs Fail, Suggests New Targets

January 27, 2022

A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer’s disease.

Cancer Drug and Antidepressants Provide Clues for Treating Fatal Brain-Eating Amoeba Infections

September 13, 2018

…identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer…

One-Two Punch: Novel Drug Pairing Could Beat Pancreatic Cancer

June 28, 2023

UC San Diego researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial

Future-proofing Software for Chemical Discovery

October 31, 2022

Computational chemistry affects everyday life more than most people might realize. It is used to develop drugs to treat diseases, generate data for environmental clean-up purposes, design solar energy technology, improve batteries, create enzymes to break down plastics and more.

Researchers Find an Unexpected Protein Function in Sea Urchin Embryo Development

November 18, 2015

…health. Cell proteins called drug transporters have been known to prevent chemotherapy and other drugs from reaching cells in disease treatment. Hamdoun and his colleagues have identified the role of a drug transporter in the early life stages of the sea urchin gut. The results could lead to new ways…

Researchers are on Their Way to Predicting What Side Effects You’ll Experience From a Drug

November 2, 2015

…California, San Diego have developed a model that could be used to predict a drug’s side effects on different patients. The proof of concept study is aimed at determining how different individuals will respond to a drug treatment and could help assess whether a drug is suitable for a particular…

DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo

October 22, 2020

UC San Diego researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer. Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

Artificial Intelligence Aids Discovery of Super Tight-Binding Antibodies

January 31, 2023

UC San Diego scientists developed an artificial intelligence tool that could accelerate the development of new high affinity antibody drugs.

3D Enzyme Model Provides New Tool for Anti-Inflammatory Drug Development

January 26, 2015

…and help drive therapeutic drug development, researchers at University of California, San Diego School of Medicine developed 3D computer models that show exactly how two PLA2 enzymes extract their substrates from cellular membranes. The new tool is described in a paper published online the week of Jan. 26 by the…

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