December 16, 2013
Down syndrome (DS) is a childhood condition but improved health care means that individuals with DS now routinely reach age 50 or 60 years of age, sometimes beyond. However, if they live long enough, people with Down syndrome are almost certain to develop Alzheimer’s disease.
January 27, 2022
A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer’s disease.
July 18, 2022
UC San Diego researchers tracked the evolution of a gene variant that supports cognitive health in older humans, but may have first emerged to protect against bacteria.
November 3, 2014
Every day in America roughly 10,000 people turn age 65. To help keep roadways safe as America grays and to help preserve the freedom of mobility of older drivers, researchers at University of California, San Diego School of Medicine are training law enforcement officers to recognize warning signs of impaired…
July 27, 2016
Ahead of the Summer Olympic Games in London four years ago, researchers reported that physical inactivity was a global pandemic that required urgent action. With the 2016 Games looming, University of California San Diego School of Medicine investigators report little change in activity levels worldwide.
September 30, 2020
Subtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete daily activities, such as managing medications or finances and other essential activities.
March 12, 2015
Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer’s disease (AD). The study, published March 12 in Cell Stem Cell, is based on experiments…
November 27, 2012
In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications – schizophrenia and bipolar disorder. In a new study, four of the antipsychotics most commonly prescribed off label for use in patients over 40 were found to…
March 28, 2019
Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, report on a novel four-year, randomized clinical trial evaluating different home-based methods to assess cognitive function and decline in participants over the age of 75.
December 2, 2019
UC San Diego Health is the first hospital in San Diego to join the Age-Friendly Health Systems initiative and be recognized as Committed to Care Excellence by the Institute for Healthcare Improvement for implementation of evidence-based interventions designed to improve care for older adults.
