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Your search for “Computational Methods” returned 588 results

This New Method Identifies Up to Twice as Many Proteins and Peptides in Mass Spectrometry Data

November 9, 2015

…of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches. The method can be applied to a range of fields, including clinical settings and fundamental biology research for cancer and other diseases. The key to the new method’s…

Computational Tools Fuel Reconstruction of New and Improved Bird Family Tree

April 1, 2024

Using computational methods and supercomputing infrastructure at UC San Diego, researchers have built the largest and most detailed bird family tree to date—an intricate chart delineating 93 million years of evolutionary relationships between 363 bird species, representing 92% of all bird families.

UC San Diego Physicist and Psychologist Awarded $7.5M by NIH for New Alzheimer’s Detection Method

November 21, 2023

UC San Diego’s Center for Scientific Computation in Imaging has received a $7.5 million grant from the National Institutes of Health to continue its interdisciplinary exploration of diffusion magnetic resonance imaging (dMRI) work related to Alzheimer’s disease.

Engineers complete first comprehensive mesh-free numerical simulation of skeletal muscle tissue

September 30, 2014

Engineers at the University of California, San Diego, have completed the first comprehensive numerical simulation of skeletal muscle tissue using a method that uses the pixels in an image as data points for the computer simulation—a method known as mesh-free simulation.

Measuring Cell-Cell Forces Using Snapshots from Time-Lapse Videos of Cells

November 5, 2019

A new computational method can measure the forces cells exert on each other by analyzing time-lapse videos of cell colonies. It could enable researchers to gain fundamental insights into what role intercellular forces play in cellular biology and how they differ in healthy and diseased states.

Research Team Quantifies ‘The Difficulties of Reproducibility’

November 27, 2013

A key pillar of “the scientific method” is reproducibility, one way to prove another scientist’s experimental claims. If the experiment and its results can be reproduced, the validity of the work is considerably strengthened.

Computer Scientists Find Way to Make All That Glitters More Realistic in Computer Graphics

July 25, 2016

…the University of California San Diego, have created a method to improve how computer graphics software reproduces the way light interacts with extremely small details, called glints, on the surface of a wide range of materials, including metallic car paints, metal finishes for electronics and injection-molded plastic finishes.

Study Provides Framework for 1 Billion Years of Green Plant Evolution

October 23, 2019

An international consortium of nearly 200 plant scientists, including engineers at UC San Diego, has released gene sequences for more than 1100 plant species, the culmination of a nine-year research project. The advance was made possible in large part thanks to new computational tools.

A Scalable Approach to Building and Updating Phylogenies

July 27, 2023

A team of researchers led by Metin Balaban and Siavash Mirarab at UC San Diego have developed a more scalable method to infer phylogenetic trees. Their work appears in Nature Biotechnology.

UC San Diego Chemists Take Aim at Drug Predictions

June 27, 2019

UC San Diego chemists offer new system to ease the synthesis and evaluation of the algorithms, the chemistry and the technology needed to predict the bound poses of ligands within a targeted protein—a necessity for designing new drugs.

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