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Your search for “Chromosomes” returned 111 results

Tethering of Shattered Chromosomal Fragments Paves Way for New Cancer Therapies

June 15, 2023

UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations

Wait for Me: Cell Biologists Decipher Signal that Ensures No Chromosome is Left Behind

January 6, 2021

Biologists have unraveled the mystery of how chromosomes are inherited correctly every time a cell divides. They discovered how a “matchmaker” molecule stops cell division until components are ready to be split. Alterations in the process can result in birth defects and certain cancers.

Biology Students Join Hundreds of Undergraduates Across Nation to Co-Author Genomics Research Paper

May 14, 2015

…evolution of an unusual chromosome in fruit flies. It was made possible by the Genomics Education Partnership, a Howard Hughes Medical Institute-funded collaboration with the biology department and Genome Sequencing Center of Washington University in St. Louis, which coordinated the work. “This collaboration provided a genuine research experience in our…

“Open” Stem Cell Chromosomes Reveal New Possibilities for Diabetes

April 2, 2015

…California, San Diego School of Medicine have discovered that chromosomes in laboratory stem cells open slowly over time, in the same sequence that occurs during embryonic development. It isn’t until certain chromosomal regions have acquired the “open” state that they are able to respond and become liver or pancreatic cells.

Machinery Used in Basic Cell Division Does Double Duty as Builder of Neurons

February 28, 2019

Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego have identified an entirely new mechanism underlying the development and structure of the nervous system during embryogenesis.

New Insights into 3D Genome Organization and Genetic Variability

February 18, 2015

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren’t encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of…

Netflix-Style Algorithm Builds Blueprint of Cancer Genomes

June 15, 2022

The science behind predicting your viewing habits on Netflix could one day be used to guide doctors in managing some of the hardest-to-treat cancers, shows a study led by the University of California San Diego and University College London.

Researchers Assemble the First Complete Human Genome

March 31, 2022

An international research team, including University of California San Diego computer scientists, has published the first complete genome. The work was done by the Telomere to Telomere (T2T) consortium, and six papers describing the project will be published April 1 in a special edition of Science.

For the Perfect Eggs, Roundworms Use Small RNAs

March 24, 2016

All multicellular organisms that reproduce sexually rely on eggs to support early life. Researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research used the tiny roundworm C. elegans as a model to better understand how eggs enable embryonic development, using only the materials already present…

Breaking Bad: How Shattered Chromosomes Make Cancer Cells Drug-Resistant

December 23, 2020

UC San Diego and Ludwig Cancer Research scientists describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.

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