April 29, 2014
…has found many somatic mutations – permanent changes in cells other than reproductive ones – that arose during the woman’s lifetime. Led by Erik Sistermans and Henne Holstege from the VU University Medical Center in Amsterdam, the team recently published its findings in the journal Genome Research as reported by…
November 6, 2017
A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease. Researchers present their findings in the…
November 10, 2014
Imagine being able to recognize your car as your own but never being able to remember where you parked it. Researchers at University of California, San Diego School of Medicine have induced this all-too-common human experience permanently in rats and from what is observed perhaps derive clues about why strokes…
July 19, 2023
What causes certain individuals who experience a sudden decline in kidney function to develop kidney disease while others recover? A new study co-led by UC San Diego bioengineers could provide insight—at the single-cell level—into the underlying factors contributing to these divergent outcomes.
September 22, 2022
With a $126 million grant from the National Institutes of Health, a multi-institution team of researchers at UC San Diego, Salk Institute and elsewhere has launched a new Center for Multiomic Human Brain Cell Atlas to describe human brain cells in unprecedented detail over a lifetime.
February 18, 2015
Nearly every cell in our bodies carries the same genetic code. Yet different types of cells read the same DNA in widely different ways, influenced by chemical chemical tags that modify the genetic material without changing the underlying DNA sequence. Scientists today announced significant progress in the unraveling of the…
October 13, 2023
In a large, multi-institutional effort led by University of California San Diego, researchers have analyzed more than a million human brain cells and revealed links between specific types of cells and various common neuropsychiatric disorders.
December 19, 2013
Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.
November 20, 2019
UC San Diego researchers describe how circular extrachromosomal DNA in cancer cells boosts aggressiveness and resistance to therapies.
November 14, 2019
Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.
