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Your search for “Cancer Target” returned 486 results

Evolution May Be to Blame for High Risk of Advanced Cancers in Humans

December 8, 2020

Compared to chimpanzees, our closest evolutionary cousins, humans are particularly prone to developing advanced carcinomas — the type of tumors that include prostate, breast, lung and colorectal cancers — even in the absence of known risk factors, such as genetic predisposition or tobacco use.

New Cancer Immunotherapy Approach Turns Immune Cells into Tiny Anti-Tumor Drug Factories

December 4, 2018

In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs.

Drug Suppresses Spread of Breast Cancer Caused by Stem-like Cells

December 11, 2017

…play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center researchers.

Precision Medicine Identifies Key Recurring Mutation in Head and Neck Cancers

July 30, 2020

Researchers at UC San Diego School of Medicine and Moores Cancer Center report that an investigational drug candidate called tipifarnib showed promise in treating key recurring mutation in head and neck cancers.

New Way to Target – And Kill – Proliferating Tumors

November 14, 2011

…UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors. The discovery, published in the November 13 online issue of the journal Nature Medicine, points to an effective, alternative method for killing fast-growing cancer cells without causing some…

Novel Imaging Model Helps Reveal New Therapeutic Target for Pancreatic Cancer

June 6, 2016

…most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. In a new study, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an…

Plant Virus Plus Immune Cell-Activating Antibody Clear Colon Cancer in Mice, Prevent Recurrence

June 21, 2022

A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system’s “natural killer” cells, shows a study by UC San Diego researchers. In mouse models of colon cancer, the therapy eliminated all tumors and prevented their recurrence.

Depriving Deadly Brain Tumors of Cholesterol May Be Their Achilles’ Heel

October 13, 2016

…California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival…

Discovery Provides Blueprint for New Drugs That Can Inhibit Hepatitis C Virus

March 19, 2012

…people worldwide and causes chronic liver disease and liver cancer.

UC San Diego-Human Longevity Inc. Agreement Seeks to Accelerate Medical Science

March 4, 2014

The new collaborative research agreement between Human Longevity Inc. (HLI) and the University of California, San Diego, announced today, represents a significant and necessary step in efforts to research and translate the potential of the human genome into novel and real treatments and therapies able to change and improve the…

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