January 24, 2019
Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.
July 28, 2014
A study of juvenile rat brain cells suggests that the effects of a commonly used anesthetic drug on the connections between brain cells are temporary.
May 4, 2016
…distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to different types of brain malignancies.
January 13, 2016
Researchers at University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego have created the first stem cell-derived in vitro cellular model of a rare, but devastating, neurodegenerative condition called Cockayne syndrome (CS).
February 11, 2015
To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease. Their study, published Feb. 10 in The Journal of Neuroscience, reveals how…
September 8, 2015
…a comprehensive approach to brain research. First, on Sept. 12, is an education and advocacy forum for the public bringing together those affected by Alzheimer’s disease, Parkinson’s disease, brain injury, stroke, epilepsy, autism, mental illness or depression. Then on Sept. 19 a research symposium will connect local “neurotechnology” innovators to…
November 10, 2014
Imagine being able to recognize your car as your own but never being able to remember where you parked it. Researchers at University of California, San Diego School of Medicine have induced this all-too-common human experience permanently in rats and from what is observed perhaps derive clues about why strokes…
July 17, 2024
UC San Diego researchers have uncovered the roots of group behavior in the brains of schooling fish. Glassfish, they found, depend on their sense of vision to coordinate social swimming behavior in schools and increase their ability to follow coordinated group movements as they mature.
May 2, 2022
UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.
April 11, 2016
…of amyloid-beta, a protein fragment that accumulates in the brains of people with Alzheimer’s disease.
