October 30, 2023
UC San Diego engineers have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins. The nanoparticles can be tailored for various applications, ranging from targeted drug delivery to neutralizing biological agents.
November 20, 2015
Engineers at the University of California, San Diego developed a new technology that uses an oscillating electric field to easily and quickly isolate drug-delivery nanoparticles from blood. The technology could serve as a general tool to separate and recover nanoparticles from other complex fluids for medical, environmental, and industrial applications.
November 30, 2021
UC San Diego nanoengineers developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus—a naturally efficient vehicle for delivering genetic material such as RNA inside cells.
June 16, 2021
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed.
November 25, 2014
The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.
May 5, 2022
…setting. They’re also engineering nanoparticles that could target the portion of the patient’s brain that was injured, delivering specific therapeutics to treat the injury and improve the patient’s long-term quality of life. “It’s really a dire state for these patients, and TBI is unfortunately quite prevalent,” said Kwon. “Patients with…
September 16, 2015
Nanoparticles disguised as human platelets could greatly enhance the healing power of drug treatments for cardiovascular disease and systemic bacterial infections. These nanoparticles are capable of delivering drugs to targeted sites in the body — particularly injured blood vessels and organs infected by harmful bacteria. This targeted drug delivery greatly…
June 12, 2024
UC San Diego engineers have developed microscopic robots, known as microrobots, that swim through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in mice, where it inhibited the growth and spread of tumors that had metastasized to the lungs, thereby boosting survival rates…
May 20, 2019
Imagine a technology that could target pesticides to treat specific spots deep within the soil, making them more effective at controlling infestations while limiting their toxicity to the environment. Researchers at UC San Diego and Case Western Reserve University have taken a step toward that goal.
May 30, 2018
The race is on between new antibiotics and drug-resistant bacteria—and scientists are challenged to keep up. By 2050, according to a Wellcome Trust study, deaths from deadly infections will be more common than cancer deaths. Scientists report that currently antimicrobial resistance causes 23,000 deaths annually in the U.S.; 700,000 deaths…
