August 30, 2023
Immunologists have uncovered new approaches to enhance protection from tumors and infections. They have revealed new insights into the metabolism of specialized cells of the immune system known as tissue-resident CD8 T cells and how they could be enhanced as immune defense weapons against tumors.
October 18, 2022
Two early career researchers at the University of California San Diego have been named recipients of the 2022 National Institutes of Health (NIH) Director’s New Innovator Award from the NIH Common Fund’s High-Risk, High-Reward Research program.
September 7, 2018
Progress in treating chronic illness, where the cause of the problem is often unknown, has lagged. Chronic conditions like cancer, diabetes and cardiovascular disease defy easy explanation, let alone remedy. In a new paper, a researcher at University of California San Diego School of Medicine, posits that chronic disease is…
October 10, 2013
Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites – small molecules produced by cellular metabolism – that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.
August 25, 2020
UC San Diego researchers engineered fluorescent tools that combine the gene editing technique CRISPR and biosensor technologies to look inside cells in a whole new way. Their findings show that a major protein that binds to the signaling molecule cAMP can form membraneless organelles in human cells.
October 30, 2015
The brain cells of patients with bipolar disorder, a manic-depressive illness characterized by severe swings in mood, energy and ability to carry out daily tasks, are more sensitive to stimuli than other people’s brain cells, reports an international team of scientists headed by researchers at Salk Institute for Biological Studies…
April 27, 2023
Researchers have developed a biosynthetic “clock” that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
December 7, 2015
Currently, there is no treatment to halt the progression of Huntington’s disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope…
December 6, 2018
Researchers spent two years testing chemical compounds for their ability to inhibit the malaria parasite at an earlier stage in its lifecycle than most current drugs, revealing a new set of chemical starting points for the first drugs to prevent malaria instead of just treating the symptoms.
February 15, 2022
UC San Diego Health researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pandemic, discovering fewer of the former and more of the latter as patients delayed care.
