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Your search for “Mitochondria” returned 81 results

How Obesity Dismantles Our Mitochondria

January 29, 2024

…found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.

Gulf War Illness Caused by Mitochondrial Dysfunction, Not Inflammation

July 12, 2023

UC San Diego scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria.

Moderate Levels of ‘Free Radicals’ Found Beneficial to Healing Wounds

October 13, 2014

…generated by the cell’s mitochondria—the energy producing structures in the cell—are actually beneficial to healing wounds. That’s the conclusion of biologists at UC San Diego who discovered that “reactive oxygen species”—chemically reactive molecules containing oxygen, such as peroxides, commonly referred to as free radicals—are necessary for the proper healing of…

Faulty DNA Disposal System Causes Inflammation

February 8, 2024

Each cell features mtDNA, instructions that mitochondria use to create energy. When mtDNA remains where it belongs, cells remain healthy. But when it goes where it doesn’t belong, mtDNA can initiate an immune response and inflammation. Scientists have discovered the pathways behind this process.

How Trauma Gets Under the Skin

April 15, 2024

Traumatic experiences in early childhood can cause metabolic changes that impact muscle function later in life, according to new research co-authored by UC San Diego professor Anthony Molina.

Breaking Bad Mitochondria

April 15, 2014

Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long.

Cocoa May Enhance Skeletal Muscle Function

March 2, 2012

…advanced heart failure and type 2 diabetes showed improved mitochondrial structure after three months of treatment with epicatechin-enriched cocoa. Epicatechin is a flavonoid found in dark chocolate.

Blood Testing Identifies Biomarkers of Suicidal Thoughts

December 15, 2023

Researchers from University of California San Diego have found that people with depression and suicidal ideation have compounds in their blood that could help identify people at higher risk of becoming suicidal. They also found sex-based differences in how depression impacts metabolism.

Molecular “Brake” Prevents Excessive Inflammation

February 25, 2016

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as…

Getting Rid of Old Mitochondria

June 16, 2014

…Krieger Institute have discovered that some neurons transfer unwanted mitochondria – the tiny power plants inside cells – to supporting glial cells called astrocytes for disposal.

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