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Your search for “Metabolism” returned 365 results

UC San Diego Chemists Develop Reversible Method of Tagging Proteins

September 16, 2012

Chemists at UC San Diego have developed a method that for the first time provides scientists the ability to attach chemical probes onto proteins and subsequently remove them in a repeatable cycle.

How Trauma Gets Under the Skin

April 15, 2024

Traumatic experiences in early childhood can cause metabolic changes that impact muscle function later in life, according to new research co-authored by UC San Diego professor Anthony Molina.

Knocking Out Key Protein in Mice Boosts Insulin Sensitivity

November 10, 2011

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

International Consortium Builds ‘Google Map’ of Human Metabolism

March 4, 2013

…has produced the most comprehensive virtual reconstruction of human metabolism to date. Scientists could use the model, known as Recon 2, to identify causes of and new treatments for diseases like cancer, diabetes and even psychiatric and neurodegenerative disorders.

Opposite Effect: Protein Widely Known to Fight Tumors Also Boosts Cancer Growth

January 31, 2019

UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” found that the human protein also plays a role in promoting tumors, in addition to suppressing them.

Century-Old Drug Reverses Autism-like Symptoms in Fragile X Mouse Model

January 15, 2015

Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study published in this week’s online issue of Molecular Autism, suggests that a genetic form of autism-like…

Peptide Improves Glucose and Insulin Sensitivity, Lowers Weight in Mice

February 7, 2018

Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.

Sedentary Behavior Increases Mortality Risk

February 28, 2024

According to new research from UC San Diego, sitting for long hours without breaks increases risk of death.

UC San Diego Cancer Scientists Identify New Drug Target for Multiple Tumor Types

July 11, 2019

A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it’s disabled or depleted in mouse models, tumors shrank significantly.

Single Dose Reverses Autism-like Symptoms in Mice

June 17, 2014

In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of…

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