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Your search for “Metabolism” returned 371 results

Nutrients Turn on Key Tumor Signaling Molecule, Fueling Resistance to Cancer Therapy

July 13, 2015

Tumors can leverage glucose and other nutrients to resist targeted therapies directed at specific cellular molecules, according to researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research. In the study, published this week in Proceedings of the National Academy of Sciences, the team used human…

Bioengineers Visualize Fat Storage in Fruit Flies

April 14, 2022

…changes in fat (lipid) metabolism in flies after they were put on a wide range of different diets. The diets included calorie-restricted diets, high protein diets, and diets with twice, four-times, and ten-times the sugar of a standard diet. "With our new optical microscopy system, we can see both where…

Molecular economics: New computer models calculate systems-wide costs of gene expression

August 7, 2012

…have developed a method of modeling, simultaneously, an organism’s metabolism and its underlying gene expression. In the emerging field of systems biology, scientists model cellular behavior in order to understand how processes such as metabolism and gene expression relate to one another and bring about certain characteristics in the larger…

Metabolism of Autism Reveals Developmental Origins

May 10, 2024

New insights into the metabolism of autism from researchers at UC San Diego could help inform early detection and prevention strategies for the disorder.

Insulin Resistance, Inflammation and a Muscle-Saving Protein

May 1, 2012

…of the journal Cell Metabolism, researchers at the University of California, San Diego School of Medicine publish three distinct articles exploring: the complex interactions of lipids and inflammation in insulin resistance; the roles of omega 3 fatty acids and a particular gene in fighting inflammation;how elevated levels of a particular…

Innovative Microscopy Demystifies Metabolism of Alzheimer’s

April 23, 2024

Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.

Maternal Programming During Pregnancy Induces Long-Term Postpartum Obesity

January 8, 2019

In a new study using a mouse model, researchers at University of California San Diego School of Medicine suggest that long-term postpartum weight gain may be due not so much to retained fat as to reprogramming of maternal energy metabolism.

New Findings on Fat Cell Metabolism Could Lead to New Approaches for Treating Diabetes and Obesity

November 16, 2015

…Diego report new insights into what nutrients fat cells metabolize to make fatty acids. The findings pave the way for understanding potential irregularities in fat cell metabolism that occur in patients with diabetes and obesity and could lead to new treatments for these conditions.

Bioengineering Professor Christian Metallo Receives 2017 Camille Dreyfus Teacher-Scholar Award

May 11, 2017

Christian Metallo, a bioengineering professor at the University of California San Diego, has been named a Camille Dreyfus Teacher-Scholar. Metallo is one of 13 faculty members nationwide to receive the honor from the Camille and Henry Dreyfus Foundation.

Research Uncovers How ‘Non-professional’ Cells Can Trigger Immune Response

May 26, 2021

Researchers are finding new details on the complex dynamics involved in how organisms sense an infection from pathogens. The researchers found that worms can sense changes in their metabolism in order to unleash protective defenses, even if they don’t directly sense an incursion from pathogens.

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