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Your search for “Metabolism” returned 360 results

Nutrients Turn on Key Tumor Signaling Molecule, Fueling Resistance to Cancer Therapy

July 13, 2015

Tumors can leverage glucose and other nutrients to resist targeted therapies directed at specific cellular molecules, according to researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research. In the study, published this week in Proceedings of the National Academy of Sciences, the team used human…

Bioengineers Visualize Fat Storage in Fruit Flies

April 14, 2022

…changes in fat (lipid) metabolism in flies after they were put on a wide range of different diets. The diets included calorie-restricted diets, high protein diets, and diets with twice, four-times, and ten-times the sugar of a standard diet. "With our new optical microscopy system, we can see both where…

Blood Testing Identifies Biomarkers of Suicidal Thoughts

December 15, 2023

Researchers from University of California San Diego have found that people with depression and suicidal ideation have compounds in their blood that could help identify people at higher risk of becoming suicidal. They also found sex-based differences in how depression impacts metabolism.

Supplementation with Amino Acid Serine Eases Neuropathy in Diabetic Mice

January 25, 2023

Working with mice, Salk Institute researchers, in collaboration with the University of California San Diego, have identified another factor contributing to diabetes-associated peripheral neuropathy: altered amino acid metabolism.

Molecular economics: New computer models calculate systems-wide costs of gene expression

August 7, 2012

…have developed a method of modeling, simultaneously, an organism’s metabolism and its underlying gene expression. In the emerging field of systems biology, scientists model cellular behavior in order to understand how processes such as metabolism and gene expression relate to one another and bring about certain characteristics in the larger…

New Research from UC San Diego Sheds Light on the Possible Origins of Life

May 18, 2023

Researchers at the University of California San Diego have identified the conditions for cell metabolism to emerge on the early Earth, shedding new light on the origins of life itself, along with the fundamental nature of biological carbon fixation.

Insulin Resistance, Inflammation and a Muscle-Saving Protein

May 1, 2012

…of the journal Cell Metabolism, researchers at the University of California, San Diego School of Medicine publish three distinct articles exploring: the complex interactions of lipids and inflammation in insulin resistance; the roles of omega 3 fatty acids and a particular gene in fighting inflammation;how elevated levels of a particular…

How Trauma Gets Under the Skin

April 15, 2024

Traumatic experiences in early childhood can cause metabolic changes that impact muscle function later in life, according to new research co-authored by UC San Diego professor Anthony Molina.

Maternal Programming During Pregnancy Induces Long-Term Postpartum Obesity

January 8, 2019

In a new study using a mouse model, researchers at University of California San Diego School of Medicine suggest that long-term postpartum weight gain may be due not so much to retained fat as to reprogramming of maternal energy metabolism.

New Findings on Fat Cell Metabolism Could Lead to New Approaches for Treating Diabetes and Obesity

November 16, 2015

…Diego report new insights into what nutrients fat cells metabolize to make fatty acids. The findings pave the way for understanding potential irregularities in fat cell metabolism that occur in patients with diabetes and obesity and could lead to new treatments for these conditions.

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