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Your search for “drug development” returned 1008 results

Coronavirus Massive Simulations Completed on Supercomputer

March 26, 2020

…computer model is being developed by the Amaro Lab of UC San Diego on the NSF-funded Frontera supercomputer of TACC at UT Austin. Biochemist Rommie Amaro hopes to build on her recent success with all-atom influenza virus simulations (left) and apply them to the coronavirus (right). Credit: Lorenzo Casalino (UC…

SDSC Team Develops Multi-scale Simulation Software for Chemistry Research

February 19, 2014

…Center at the University of California, San Diego, have developed software that greatly expands the types of multi-scale QM/MM (mixed quantum and molecular mechanical) simulations of complex chemical systems that scientists can use to design new drugs, better chemicals, or improved enzymes for biofuels production.

Two Novel Biobanks Offer Investigatory Targets for Cocaine and Oxycodone Addiction

April 26, 2021

Researchers have created to novel biobanks of diverse tissues from animals to further explore the biological bases and consequences of addiction to cocaine and oxycodone.

New Therapeutic Target Discovered for Alzheimer’s Disease

March 17, 2014

…peptides linked to Alzheimer’s disease. Moreover, the candidate inhibitor drug has been shown to be safe in humans.

CHO Systems Biology Center Pioneers Efforts to Improve Cell Production of High-Value Pharmaceuticals

April 13, 2017

…lines to accelerate biologic drug development is a goal of the CHO Systems Biology Center at the University of California San Diego Jacobs School of Engineering. Center researchers are developing new technologies and training the next generation of cell line engineers and systems biology specialists to advance CHO cell engineering…

Half a Million Tests and Many Mosquitoes Later, New Buzz about a Malaria Prevention Drug

December 6, 2018

Researchers spent two years testing chemical compounds for their ability to inhibit the malaria parasite at an earlier stage in its lifecycle than most current drugs, revealing a new set of chemical starting points for the first drugs to prevent malaria instead of just treating the symptoms.

Study Uncovers Why Heart Attack Triggers Arrhythmia in Some, Explores Potential Treatment

January 28, 2019

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

SDSC Researchers Develop Potential COVID-19 Protease Inhibitors

April 15, 2020

UC San Diego researchers recently created a pharmacophore model and conducted data mining of the conformational database of FDA-approved drugs that identifies 64 compounds as potential inhibitors of the COVID-19 protease.

Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

February 18, 2021

Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.

Do a Mom’s Medications Affect Her Breast Milk and Baby? New Center Investigates

September 10, 2021

UC San Diego School of Medicine receives $6.1M to launch a new research center studying the effects of maternal antibiotic use on breast milk and infant health. The center is funded by National Institutes of Health, as part of their new Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub.

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