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Your search for “Stem Cells” returned 506 results

Looking Back and Ahead, Shiley’s Vision Remains Clear

February 26, 2015

…to pathology, neurosciences and stem cell research, to improve the treatment of eye diseases, find new cures and hasten the day when blindness is entirely preventable.” The institute will include the new Richard C. Atkinson Laboratory for Regenerative Ophthalmology, created last year with an anonymous $6.5 million gift from a…

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

August 25, 2021

Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.

Regulating Single Protein Prompts Fibroblasts to Become Neurons

January 10, 2013

…in ordinary fibroblasts is sufficient to directly convert the cells into functional neurons. The findings, which could have far-reaching implications for the development of new treatments for neurodegenerative diseases like Huntington’s, Parkinson’s and Alzheimer’s, will be published online in advance of the January 17 issue of the journal Cell.

Reprogrammed Stem Cell-Derived Neurons Survive Long-Term in Pigs with Spinal Cord Injuries

May 9, 2018

…Diego School of Medicine describe successfully grafting induced pluripotent stem cell (iPSC)-derived neural precursor cells back into the spinal cords of genetically identical adult pigs with no immunosuppression efforts. The grafted cells survived long-term, displayed differentiated functionality and caused no tumors.

3D Printed Implant Promotes Nerve Cell Growth to Treat Spinal Cord Injury

January 14, 2019

For the first time, researchers at University of California San Diego have used rapid 3D printing technologies to create a spinal cord, then successfully implanted that scaffolding, loaded with neural stem cells, into sites of severe spinal cord injury in rats.

Vulnerability Identified for Subtypes of Glioblastoma

November 30, 2017

…In a paper published online in the journal Cancer Cell on November 30, University of California San Diego School of Medicine researchers identified a strategy that pinpoints a genetically distinct subpopulation of patients with glioblastoma that is particularly sensitive to drugs like cilengitide that target a cell adhesion receptor known…

Embryonic Brain Overgrowth Dictates Autism Severity, New Research Suggests

June 17, 2024

Researchers at UC San Diego found an unusually large brain may be the first sign of autism and visible as early as the first trimester.

Depriving Deadly Brain Tumors of Cholesterol May Be Their Achilles’ Heel

October 13, 2016

…Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models.

Helmsley Charitable Trust Grants UC San Diego $4.7M to Study Crohn’s Disease

May 9, 2019

…a transdisciplinary team of cellular, molecular and stem-cell biologists along with computer science engineers, pathologists and gastroenterologists. Together, they will build and validate a stem cell-based “gut-in-a-dish” model of Crohn’s disease, as a “Phase 0” human model before clinical trials. Pradipta Ghosh The stem cells will be derived from intestinal…

Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing

August 31, 2021

UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.

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