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Your search for “Genomics” returned 711 results

New Algorithm Reveals Extremely High Mutations Rates in Complex Genomic Regions

August 16, 2023

In a paper published this week in the journal Nature Methods, UC San Diego researchers shared a new UniAligner algorithm for comparing highly repetitive genomic regions.

Understanding a Protein’s Role in Familial Alzheimer’s Disease

November 14, 2013

Researchers at the University of California, San Diego School of Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer’s disease (AD), discovering that simple loss-of-function does not contribute to the inherited form…

GenomeSpace “Recipes” Help Biologists Interpret Genomic Data

January 20, 2016

…Medicine and collaborators developed GenomeSpace, a cloud-based, biologist-friendly platform that connects more than 20 bioinformatics software packages and resources for genomic data analysis. The team is now developing and crowdsourcing “recipes” — step-by-step workflows — to better enable non-programming researchers to interpret their genomic data. The work is described in…

Illumina Supports Enhanced Genomics-Enabled Discovery and Training Programs at UC San Diego

August 4, 2022

Illumina Supports Enhanced Genomics-Enabled Discovery and Training Programs at UC San Diego New laboratory automation technology will advance marine biomedical research, preparing students for biotech workforce The Illumina Laboratory in Scholander Hall is one of two new automation Hubbs on the Scripps Oceanography campus. Photos by Erik Jepsen/University Communications. Scripps…

Long-Reads and Powerful Algorithms Identify “Invisible” Microbes

January 3, 2022

Researchers have shown that highly accurate, long-read genomic sequencing technology (HiFi), combined with advanced algorithms, can differentiate between nearly identical organisms, allowing researchers to more completely catalogue microbial communities.

Blood Biopsy Reveals Unique, Targetable Genetic Alterations in Patients with Rare Cancer

August 15, 2017

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

Single-Cell Genome Sequencing Gets Better

November 12, 2013

…of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

Five Cutting-edge Advances in Biomedical Engineering and Their Applications in Medicine

February 21, 2024

Innovations in the form of multi-scale sensors and devices, creation of humanoid avatars and the development of exceptionally realistic predictive models driven by AI can radically change our lifestyles and response to pathologies.

Epigenetics Alters Genes in Rheumatoid Arthritis

July 3, 2012

Researchers at the University of California, San Diego – led by Gary S. Firestein, MD, professor in the Division of Rheumatology, Allergy and Immunology at UC San Diego School of Medicine – investigated a mechanism usually implicated in cancer and in fetal development, called DNA methylation, in the progression of…

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

October 19, 2021

An international team of researchers has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

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