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Your search for “Computational Methods” returned 633 results

Computational Strategy Helps to Map Human Epigenome

February 18, 2015

Nearly every cell in our bodies carries the same genetic code. Yet different types of cells read the same DNA in widely different ways, influenced by chemical chemical tags that modify the genetic material without changing the underlying DNA sequence. Scientists today announced significant progress in the unraveling of the…

Supercomputer Models Describe Chloride’s Role in Corrosion

January 5, 2021

Simulations conducted using the Comet supercomputer at UC San Diego’s San Diego Supercomputer Center provide new insights on how chloride corrodes structural metals, causing severe economic and environmental impacts.

New Method Makes Better Predictions of Material Properties Using Low Quality Data

January 14, 2021

By combining large amounts of low-fidelity data with smaller quantities of high-fidelity data, nanoengineers at UC San Diego have developed a machine learning method to more accurately predict the properties of new materials including, for the first time, disordered materials.

Computational Tools Fuel Reconstruction of New and Improved Bird Family Tree

April 1, 2024

Using computational methods and supercomputing infrastructure at UC San Diego, researchers have built the largest and most detailed bird family tree to date—an intricate chart delineating 93 million years of evolutionary relationships between 363 bird species, representing 92% of all bird families.

Jill P. Mesirov Appointed Associate Vice Chancellor for Computational Health Sciences

June 24, 2015

Leading computational biologist Jill P. Mesirov, PhD, has been appointed associate vice chancellor for computational health sciences and professor of medicine at University of California, San Diego School of Medicine and Moores Cancer Center. Mesirov most recently served as associate director and chief informatics officer at the Broad Institute of…

A Scalable Approach to Building and Updating Phylogenies

July 27, 2023

A team of researchers led by Metin Balaban and Siavash Mirarab at UC San Diego have developed a more scalable method to infer phylogenetic trees. Their work appears in Nature Biotechnology.

Gene Editing Technique Helps Find Cancer’s Weak Spots

March 20, 2017

…of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published March 20 in Nature Methods, uncovered 120 new opportunities for cancer drug development.

UC San Diego School of Medicine Researchers Receive $5 Million in Type 1 Diabetes Grants

October 24, 2016

There are many unanswered questions about the mechanisms that contribute to the onset of type 1 diabetes. Researchers at University of California San Diego School of Medicine hope to answer some of them with two Type 1 Diabetes Special Statutory Funding Program grants from the National Institutes of Health totaling…

Engineers Develop Methods to Speed Up Simulations in Computational Grand Challenge Problems

March 26, 2015

…a new family of methods to significantly increase the speed of time-resolved numerical simulations in computational grand challenge problems. Such problems often arise from the high-resolution approximation of the partial differential equations governing complex flows of fluids or plasmas. The breakthrough could be applied to simulations that include millions or…

Big Data for Chemistry

November 18, 2016

An international team of computer scientists has for the first time developed a method to find antibiotics hidden in huge but still unexplored mass spectrometry datasets. They detailed their new method, called DEREPLICATOR, in the Oct. 31 issue of Nature Chemical Biology.

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