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Your search for “Cellular Pathways” returned 184 results

Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells

June 6, 2017

Researchers at University of California San Diego School of Medicine report that cancer cells appear to communicate to other cancer cells, activating an internal mechanism that boosts resistance to common chemotherapies and promotes tumor survival.

Scientists Create Synthetic Membranes That Grow Like Living Cells

June 22, 2015

Chemists and biologists at UC San Diego have succeeded in designing and synthesizing an artificial cell membrane capable of sustaining continual growth, just like a living cell.

New Bioinformatic Analysis Reveals Role of Proteins in Diabetic Kidney Disease

November 15, 2016

A new bioinformatic framework developed by researchers at University of California San Diego School of Medicine has identified key proteins significantly altered at the gene-expression level in biopsied tissue from patients with diabetic kidney disease, a result that may reveal new therapeutic targets.

Single Gene Mutation Linked to Diverse Neurological Disorders

October 9, 2013

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other,…

Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified

November 8, 2024

Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.

New Cellular Pathway Triggering Allergic Asthma Response Identified

January 19, 2015

…identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. The discovery, they say, could point the way to new therapies that suppress the inflammatory allergic response, offering potential relief to millions of Americans with the chronic lung condition and potentially…

UC San Diego Chemists Use Light to Pinpoint Gene Expression

February 13, 2018

…chemistry graduate students activated cellular gene expression with unique precision. By modifying messenger RNA (mRNA)—a group of molecules that carries genetic information from DNA to ribosomes where specifications of gene expression occur—the chemists were able to precisely trigger gene expressions at a specific time and place using laser light. This…

Underappreciated Protein Plays Critical Role In RNA Regulation and Male Fertility

March 31, 2016

A protein once thought to be of little consequence has been found to be a central player in processes ranging from male fertility to early embryonic development, according to a study published in the March 31 online issue of Cell by researchers at the University of California, San Diego School…

Disjointed: Cell Differences May Explain Why Rheumatoid Arthritis Varies By Location

June 10, 2016

…distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA. The findings help explain why drugs treating RA vary in effect and provide a potential new template for precisely targeting treatment for each and every…

Exercise … it Does a Body Good: 20 Minutes Can Act as Anti-Inflammatory

January 12, 2017

It’s well known that regular physical activity has health benefits, including weight control, strengthening the heart, bones and muscles and reducing the risk of certain diseases. Recently, researchers at University of California San Diego School of Medicine found how just one session of moderate exercise can also act as an…

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