May 21, 2014
Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have used computer simulations of cancer cells – cancer avatars – to identify drugs most likely to kill cancer cells isolated from patients’ brain tumors.
September 5, 2016
Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington’s disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse…
December 26, 2018
Some dermal fibroblasts can convert into fat cells that reside under the dermis, giving skin a youthful look and producing peptides that fight infections. University of California San Diego School of Medicine researchers and colleagues show how this happens and what causes it to stop as people age.
August 29, 2023
A $5 million gift from the Nancy and Geoffrey Stack Foundation has established the UC San Diego Gene Therapy Initiative to find novel therapies for children and adults with genetic diseases.
May 10, 2024
New insights into the metabolism of autism from researchers at UC San Diego could help inform early detection and prevention strategies for the disorder.
October 10, 2024
Funded by a California Institute for Regenerative Medicine grant, researchers in the UC San Diego Verge Center aim to uncover the genetic mechanisms behind neuropsychiatric disorders.
January 6, 2021
Biologists have unraveled the mystery of how chromosomes are inherited correctly every time a cell divides. They discovered how a “matchmaker” molecule stops cell division until components are ready to be split. Alterations in the process can result in birth defects and certain cancers.
November 21, 2017
…have “got mail”—of the cellular sort. They know that cells have elaborate “addressing” functions that “send” proteins to the correct compartment, but they are now learning how cells “’write” the addresses and then “read” them. This is important because cellular function depends on each molecule in the cell being where…
October 1, 2012
Two proteins previously found to contribute to ALS, also known as Lou Gehrig’s disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine, shows that a common pathway links them.
April 12, 2022
How do the lungs develop after taking their first breaths outside the womb? What cellular events and changes early in life give rise to lung malfunction and disease? UC San Diego researchers developed a single-cell atlas of postnatal lung development that could help answer these questions.
