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News Archive - Skaggs School of Pharmacy and Pharmaceutical Sciences

Common Antibiotic May Be the Answer to Many Multidrug-Resistant Bacterial Infections

June 10, 2015

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors. The researchers believe the finding, published June 10 by EBioMedicine, could prompt an immediate review of the current standard of care for patients with certain so-called “superbug” infections.

Molecular Homing Beacon Redirects Human Antibodies to Fight Pathogenic Bacteria

May 6, 2015

With the threat of multidrug-resistant bacterial pathogens growing, new ideas to treat infections are sorely needed. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report preliminary success testing an entirely novel approach — tagging bacteria with a molecular “homing beacon” that attracts pre-existing antibodies to attack the pathogens.

Boosting the Body’s Natural Ability to Fight Urinary Tract Infections

April 30, 2015

Urinary tract infections (UTIs) are common, and widespread antibiotic resistance has led to urgent calls for new ways to combat them. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that an experimental drug that stabilizes a protein called HIF-1alpha protects human bladder cells and mice against a major UTI pathogen. The drug might eventually provide a therapeutic alternative or complement to standard antibiotic treatment.

3D Human Skin Maps Aid Study of Relationships Between Molecules, Microbes and Environment

March 30, 2015

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences produced 3D maps of molecular and microbial variations across the body. These maps provide a baseline for studies of the interplay between the molecules that make up our skin, our microbiomes, our personal hygiene routines and other environmental factors. The study, published March 30 by PNAS, may help further our understanding of the skin’s role in human health and disease.

Mark Harrison Appointed CFO of UC San Diego Health Sciences

March 23, 2015

Mark Harrison has been appointed as the new chief financial officer (CFO) for UC San Diego Health Sciences, effective March 23, 2015. As CFO, Mark will collaborate with university leadership to ensure the strong financial health of the globally-recognized UC San Diego Health Sciences enterprise, overseeing a budget of more than $2.4 billion.

UC San Diego and Perdana University Partner to Advance Medical Education and Research

February 2, 2015

Officials of the University of California, San Diego and Perdana University in Malaysia have announced a plan to collaborate on further development of the Perdana University Graduate School of Medicine (PUGSOM). UC San Diego was chosen from among the top schools of medicine in the United States to lead this initiative.

Pictured Together for the First Time: a Chemokine and its Receptor

January 22, 2015

Researchers at University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences and the Bridge Institute at the University of Southern California report the first crystal structure of the cellular receptor CXCR4 bound to an immune signaling protein called a chemokine. The structure answers longstanding questions about a molecular interaction that plays an important role in human development, immune responses, cancer metastasis and HIV infections.

UC San Diego School of Medicine Named One of Nation’s Top Residency Programs

January 13, 2015

UC San Diego School of Medicine was today named one of the nation’s top residency training programs in 10 specialties by Doximity. The Doximity report included more than 50,000 peer nominations from board-certified US physicians, and evaluated 3,691 residency training programs across 20 specialties.

Pieter Dorrestein Recognized by Pharmacology Society

January 12, 2015

Pieter Dorrestein, PhD, has been selected to receive the 2015 John Jacob Abel Award in Pharmacology by the American Society for Pharmacology and Experimental Therapeutics (ASPET). Dorrestein is a professor of pharmacology, chemistry and biochemistry in the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego.

Scientists Discover Neurochemical Imbalance in Schizophrenia

September 11, 2014

Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.
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